I would like to share with you the results of an in vitro test performed recently by Dr Philippa Darbre at Reading University. The test is very simple: breast cancer cells incubated for 4 days with and without 0.00019% isobutylparaben. See below the breast cancer cells before the incubation (1) and after the incubation without (2) and with isobutylparaben (3)
Picture 1
Picture 2
Picture 3
I am aware that this is an vitro test, so all the complexity of the human body is taken out of the equation, however I believe they are still valid in showing there is reason to be concerned about this compound. You can clearly see that after 4 days the breast cancer cells do grow more than the ones without. I believe that the major cancer trigger is emotional stress, however environmental factors like this can promote the cancer cells growth making it bigger.
If you add the fact that parabens do get absorbed through the skin and that they are found in urine, we need to think about their journey through the body as well as their interaction on their journey with other parts of the body. Once they are in the blood stream they are in...
Parabens are not only used in cosmetics but also in many drugs such as cough mixtures (usually they are not declared on the label), however when they get ingested they get exposed to the stomach juices and get transformed into something considered to be safe. This indicates that the parabens found in urine do come form the skin absorption rather than ingestion.
What to do as a consumer? Well my suggestion is to read the ingredients list before you buy your cosmetics in order to avoid them.
At a regulatory level isopropylparaben and butylparaben are under review and the European scientific committee has asked for more data to fill the data gaps. The industry might reply that there is no money to invest in the new research, so what might happen is the ban of these substances based on the lack of the evidence requested.
I shall keep you posted..
References:
"In vitro skin permeation and retention of parabens in cosmetic skin formulations", Pedersen, Marra, Nicoli and Santi, International Journal of Cosmetic Science 2007, 29, 361-367; "Assessment of principal parabens used in cosmetics after their passage through human epidermis-dermis layers (ex-vivo study", El Hussein S, Muret P, Berard M, Makki S, Humbert P, Exp Dermatol. 2007 Oct;16(10):830-6;
“Parabens as urinary biomarkers of exposure in humans”, Xiaoyun Ye, Amber Bishop..., Environ. Health Perspect, 114, 1843-1846
